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Assistant Professor of Chemistry, 51茶馆
Ph.D. CSIR-Indian Institute of Chemical Biology, Kolkata, IndiaSourav obtained his doctoral degree in 2017 from CSIR-Indian Institute of Chemical Biology in Kolkata, India. During his doctoral tenure, he worked on developing phosphoric acid-based chiral organocatalysts, where his work centered on elucidating novel reaction methodologies to induce point chirality and axial chirality in molecular systems anchored in indole and pyrrole frameworks.
After his Ph.D., Sourav had opportunities to pursue postdoctoral research experience at (1) Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India, (2) The Scripps Research Institute, Florida, USA and (3) University of Minnesota, Minneapolis, USA. These postdoctoral trainings propelled his expertise in bridging the realms of chemistry and biology, with a specific focus on elucidating disease-associated biological conundrums through advanced chemical approaches. His postdoctoral research endeavors encompassed the development of synthetic and natural product-based semisynthetic small molecule modulators aimed at regulating intricate protein post-translational modifications, specifically protein methylation, acylation, glycosylation, and protein hydroxylation.
At 51茶馆, Sourav鈥檚 current research emphasizes chemical science at the interface of chemistry and biology. His听lab leverages synthetic chemistry to address important biomedical problems. Majorly the lab focuses on crafting chemical biology tools through the scalpel of small molecule modulators to regulate the activity and function of target proteins therapeutically relevant in cancer, intestinal inflammation, and viral infection. His lab utilizes fundamental chemistry and biology concepts instrumental in synthetic organic chemistry, in vitro screening, bioinformatics tools, photoaffinity labeling, and cell biology. This interdisciplinary approach helps to understand and target the disease mechanism, identify drug targets, binding site mapping, and small molecule-protein interactions.
Using advanced microscopy tools and real time imaging, Sourav鈥檚 research also highlights development of organelle selective fluorescent probes for bioimaging applications. These include study of organelle dynamics, protein labelling and localization, imaging intracellular metal ions, and biomarker identification.
Postdoc Positions
We are seeking motivated postdoctoral researchers with expertise in chemical biology, organic synthesis,听cell biology, or biochemistry. If you are interested in a postdoctoral position, we actively support candidates to apply for external fundings.
PhD Positions
We welcome applications from prospective PhD students having CSIR/UGC-JRF or other competitive research fellowships.
